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rs683395

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0
(C;C) 1.3x risk
(C;T) 1.5x risk
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome3
Position183152030
GeneLAMP3
is asnp
is mentioned by
dbSNPrs683395
ebirs683395
HLIrs683395
Exacrs683395
Varsomers683395
Maprs683395
PheGenIrs683395
hapmaprs683395
1000 genomesrs683395
hgdprs683395
ensemblrs683395
gopubmedrs683395
geneviewrs683395
scholarrs683395
googlers683395
pharmgkbrs683395
gwascentralrs683395
openSNPrs683395
23andMers683395
23andMe allrs683395
SNP Nexus

SNPshotrs683395
SNPdbers683395
MSV3drs683395
GWAS Ctlgrs683395
GMAF0.1175
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs683395 has been reported in a large study to be associated with bipolar disorder.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.47 (CI 1.26-1.71), and for homozygotes, 1.3 (CI 0.69-2.46). [PMID 17554300OA-icon.png]

GWAS
SNP rs683395
PubMedID [PMID 17554300OA-icon.png]
Condition Bipolar disorder
Gene NR
Risk Allele G
pValue 5.00E-006
OR 1.47
95% CI 1.26-1.71



[PMID 19308021OA-icon.png] Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.


GET Evidence
rs683395
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.859375
summary