| Geno
|
Mag
|
Summary
|
| (A;A)
|
|
normal
|
| (A;G)
|
|
more likely to gain weight if taking risperidone
|
| (G;G)
|
|
more likely to gain weight if taking risperidone
|
rs6837793 is a SNP associated with the NPY5 receptor gene, located in the single promoter region likely to be co-regulating the Y1 and Y5 receptor genes.
In a study of 101 mostly Caucasian patients prescribed the atypical antipsychotic risperidone, carriers of a rs6837793(G) allele were more likely to gain significant weight compared to rs6837793(A;A) carriers, as assessed by physiogenomic analysis of corresponding weight profiles. Two other SNPs, rs8179183 and rs705381, were also significantly associated with weight profiles in these patients.[PMID 17199131]
[PMID 18254975
] Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat.
[PMID 18828811] Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.
] Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat.
