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rs6953165

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs6953165(C;G)
Make rs6953165(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position128938156
GeneIRF5
is asnp
is mentioned by
dbSNPrs6953165
ebirs6953165
HLIrs6953165
Exacrs6953165
Varsomers6953165
Maprs6953165
PheGenIrs6953165
hapmaprs6953165
1000 genomesrs6953165
hgdprs6953165
ensemblrs6953165
gopubmedrs6953165
geneviewrs6953165
scholarrs6953165
googlers6953165
pharmgkbrs6953165
gwascentralrs6953165
openSNPrs6953165
23andMers6953165
23andMe allrs6953165
SNP Nexus

SNPshotrs6953165
SNPdbers6953165
MSV3drs6953165
GWAS Ctlgrs6953165
GMAF0.05601
Max Magnitude0
[PMID 18311811] Japanese 277 SLE patients and 201 controls. Carriers of the rs2004640T slightly increased among SLE patients (58.8%) as compared with controls (50.2%). When data from our Japanese population were combined with previously published data from a Korean population, the T allele frequency was found to be significantly increased in SLE patients (P = 8.3 x 10(-5)). While no association was observed for the rs10954213 . significant associations with 3 intron 1 SNPs (-4001, rs6953165, and rs41298401) were found. The allele frequency of rs41298401G was significantly decreased in SLE patients (13.0% versus 18.7% in controls; P = 0.017), and the allele frequency of rs6953165G, which was in absolute linkage disequilibrium with -4001A, was increased in SLE patients (8.8% versus 5.2% in controls; P = 0.034). The Caucasian risk haplotype was not present; instead, a protective haplotype carrying rs2004640G, rs41298401G, the deletion in exon 6, and rs10954213A was identified. SNP rs10954213
Neighborrs2004640
Distance91