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rs6966915

From SNPedia

Orientationplus
Make rs6966915(C;C)
Make rs6966915(C;T)
Make rs6966915(T;T)
ReferenceGRCh38.p2 38.2/147
Chromosome7
Position12226362
GeneTMEM106B
is asnp
is mentioned by
dbSNPrs6966915
ebirs6966915
HLIrs6966915
Exacrs6966915
Varsomers6966915
Maprs6966915
PheGenIrs6966915
hapmaprs6966915
1000 genomesrs6966915
hgdprs6966915
ensemblrs6966915
gopubmedrs6966915
geneviewrs6966915
scholarrs6966915
googlers6966915
pharmgkbrs6966915
gwascentralrs6966915
openSNPrs6966915
23andMers6966915
23andMe allrs6966915
SNP Nexus

SNPshotrs6966915
SNPdbers6966915
MSV3drs6966915
GWAS Ctlgrs6966915
Max Magnitude
? (C;C) (C;T) (T;T) 28
In a study of 501 symptomatic progranulin mutation carriers and 1173 matched controls

rs696615 in TMEM106B was found to be the only SNP reaching genome wide significance in modifying the risk of frontotemporal dementia (FTD) (p= 7.89e-10, OR=0.54 [0.45-0.66]). {A gene set might include the 114 GRN mutations used in the study with rs6966915.}

Page numbered 231 below. http://onlinelibrary.wiley.com/doi/10.1111/jnc.13692/epdf