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rs706778

From SNPedia

Orientationminus
Stabilizedminus
Make rs706778(A;A)
Make rs706778(A;G)
Make rs706778(G;G)
ReferenceGRCh38 38.1/142
Chromosome10
Position6056986
GeneIL2RA
is asnp
is mentioned by
dbSNPrs706778
ebirs706778
HLIrs706778
Exacrs706778
Varsomers706778
Maprs706778
PheGenIrs706778
hapmaprs706778
1000 genomesrs706778
hgdprs706778
ensemblrs706778
gopubmedrs706778
geneviewrs706778
scholarrs706778
googlers706778
pharmgkbrs706778
gwascentralrs706778
openSNPrs706778
23andMers706778
23andMe allrs706778
SNP Nexus

SNPshotrs706778
SNPdbers706778
MSV3drs706778
GWAS Ctlgrs706778
GMAF0.4844
Max Magnitude
? (A;A) (A;G) (G;G) 28
rs706778 is mentioned as being strongly associated with type-1 diabetes in [PMID 17554300OA-icon.png]
Neighborrs2104286
Distance96
GWAS snp
PMID [PMID 20453842OA-icon.png]
Trait Rheumatoid arthritis
Title Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lock
Risk Allele T
P-val 1E-11
Odds Ratio 1.14 [NR]

[PMID 20615141] Association of the Protein Tyrosine Phosphatase Nonreceptor 22 Haplotypes with Autoimmune Thyroid Disease in the Japanese Population


[PMID 17395754] Toward further mapping of the association between the IL2RA locus and type 1 diabetes.


[PMID 18556337OA-icon.png] Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).


[PMID 18776148OA-icon.png] Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms.


[PMID 19106270] Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population.


[PMID 19956099OA-icon.png] The type I diabetes association of the IL2RA locus.


[PMID 19956101OA-icon.png] Overview of the Rapid Response data.


[PMID 22328738OA-icon.png] Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.


[PMID 22897480] Investigation of selected cytokine genes suggests that IL2RA and the TNF/LTA locus are risk factors for severe alopecia areata.


[PMID 23972291] Polymorphisms in the IL2RA and IL2RB genes in inflammatory bowel disease risk

GWAS snp
PMID [PMID 24390342OA-icon.png]
Trait Rheumatoid arthritis
Title Genetics of rheumatoid arthritis contributes to biology and drug discovery.
Risk Allele T
P-val 5E-15
Odds Ratio 1.12 [1.09-1.15]