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rs7076156

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2
(G;G) 0
Make rs7076156(A;G)
ReferenceGRCh38 38.1/141
Chromosome10
Position62655424
GeneZNF365
is asnp
is mentioned by
dbSNPrs7076156
ebirs7076156
HLIrs7076156
Exacrs7076156
Varsomers7076156
Maprs7076156
PheGenIrs7076156
hapmaprs7076156
1000 genomesrs7076156
hgdprs7076156
ensemblrs7076156
gopubmedrs7076156
geneviewrs7076156
scholarrs7076156
googlers7076156
pharmgkbrs7076156
gwascentralrs7076156
openSNPrs7076156
23andMers7076156
23andMe allrs7076156
SNP Nexus

SNPshotrs7076156
SNPdbers7076156
MSV3drs7076156
GWAS Ctlgrs7076156
GMAF0.152
Max Magnitude2
? (A;A) (A;G) (G;G) 28
[PMID 21257989OA-icon.png] Variants in ZNF365 isoform D are associated with Crohn's disease
OMIM607818
DescURIC ACID NEPHROLITHIASIS, SUSCEPTIBILITY TO
Variant0001
Relatedalso


Venter snp
Source plos
Gene ZNF365
allele G
frequency 0.792
sift
HuRef 1103649958175
Disease Association Defects in ZNF365 may be a cause of susceptibility to uric acid nephrolithiasis (UAN) (MIM:605990). UAN occurs when the urine becomes overly concentrated with uric acid that may form small crystals.



GWAS snp
PMID [PMID 22412388OA-icon.png]
Trait
Title A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
Risk Allele G
P-val 7E-9
Odds Ratio 1.1900 None


ClinVar
Risk rs7076156(G;G)
Alt rs7076156(G;G)
Reference rs7076156(A;A)
Significance Other
Disease Uric acid nephrolithiasis
Variation info
Gene ZNF365
CLNDBN Uric acid nephrolithiasis, susceptibility to
Reversed 0
HGVS NC_000010.10:g.64415184A\x3d
CLNSRC OMIM Allelic Variant
CLNACC RCV000002951.2,



GET Evidence
ZNF365-T62A
aa_change Thr62Ala
aa_change_short T62A
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency
summary