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rs708272(T;T)

From SNPedia

B2B2 genotype; some reduction in heart disease risk from moderate alcohol consumption
Is agenotype
ofrs708272
GeneCETP
Chromosome16
Position56,962,376
mentionedby
Magnitude2.2
ReputeGood
Geno Mag Summary
(C;C) 2.1 Small reduction in coronary heart disease risk from alcohol consumption
(C;T) 2.1 Small reduction in heart disease risk from drinking alcohol
(T;T) 2.2 B2B2 genotype; some reduction in heart disease risk from moderate alcohol consumption

In the 2014 publication by Mehlig et al., ([PMID 25288221OA-icon.png]), this B2B2 genotype showed the greatest reduction in coronary heart disease risk for those drinking moderate amounts of alcohol (6.5 - 13g/day for men; odds ratio 0.21) compared to those imbibing low (under 6.5g) amounts (designated as the reference, i.e. odds ratio of 1). The odds ratios for B2B2 genotypes either abstaining or drinking higher amounts (over 13.5g/day) were also lower, at 0.76 and 0.48, respectively.