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rs7120118

From SNPedia

Orientationplus
Stabilizedplus
Make rs7120118(C;C)
Make rs7120118(C;T)
Make rs7120118(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position47264739
GeneNR1H3
is asnp
is mentioned by
dbSNPrs7120118
ebirs7120118
HLIrs7120118
Exacrs7120118
Varsomers7120118
Maprs7120118
PheGenIrs7120118
hapmaprs7120118
1000 genomesrs7120118
hgdprs7120118
ensemblrs7120118
gopubmedrs7120118
geneviewrs7120118
scholarrs7120118
googlers7120118
pharmgkbrs7120118
gwascentralrs7120118
openSNPrs7120118
23andMers7120118
23andMe allrs7120118
SNP Nexus

SNPshotrs7120118
SNPdbers7120118
MSV3drs7120118
GWAS Ctlgrs7120118
GMAF0.4637
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19060910OA-icon.png]
Trait HDL cholesterol
Title Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
Risk Allele G
P-val 4E-8
Odds Ratio 0.04 [0.03-0.05] mmol/l increase


The C allele of this SNP in the NR1H3 gene is associated with increased (but still low) risk of progressive supranuclear palsy. [PMID 17357082OA-icon.png]


[PMID 22029530OA-icon.png] A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia


[PMID 22027013] Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease


[PMID 19299407OA-icon.png] Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.


[PMID 21562465OA-icon.png] Liver X receptor alpha gene polymorphisms and variable cardiovascular outcomes in patients treated with antihypertensive therapy: results from the INVEST-GENES study.


GET Evidence
rs7120118
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.359375
summary



[PMID 23838803] Association of liver X receptors (LXRs) genetic variants to gallbladder cancer susceptibility


[PMID 27070640] MADD-FOLH1 Polymorphisms and Their Haplotypes with Serum Lipid Levels and the Risk of Coronary Heart Disease and Ischemic Stroke in a Chinese Han Population