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rs7142143

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2.5 Increased odds of relapse in treated childhood ALL patients
(C;T) 2 Increased odds of relapse in treated childhood ALL patients
(T;T) 0 common/normal
ReferenceGRCh38 38.1/141
Chromosome14
Position50936813
GenePYGL
is asnp
is mentioned by
dbSNPrs7142143
ebirs7142143
HLIrs7142143
Exacrs7142143
Varsomers7142143
Maprs7142143
PheGenIrs7142143
hapmaprs7142143
1000 genomesrs7142143
hgdprs7142143
ensemblrs7142143
gopubmedrs7142143
geneviewrs7142143
scholarrs7142143
googlers7142143
pharmgkbrs7142143
gwascentralrs7142143
openSNPrs7142143
23andMers7142143
23andMe allrs7142143
SNP Nexus

SNPshotrs7142143
SNPdbers7142143
MSV3drs7142143
GWAS Ctlgrs7142143
GMAF0.0225
Max Magnitude2.5
? (C;C) (C;T) (T;T) 28
[PMID 23007406OA-icon.png] Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia. Each rs7142143(C) allele increases odds of relapse by 3.6x (CI: 2.34-5.57, adjusted p=1.20 × 10e−5) based on a study of 2,500 childhood acute lymphoblastic leukemia patients.
GWAS snp
PMID [PMID 23007406OA-icon.png]
Trait Acute lymphoblastic leukemia (childhood)
Title Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia.
Risk Allele C
P-val 7E-9
Odds Ratio 3.61 [2.34-5.57]