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rs7151526(A;A)

From SNPedia

possible increased risk for ANCA associated vasculitis
Is agenotype
ofrs7151526
GeneSERPINA1
Chromosome14
Position94,397,299
mentionedby
Magnitude1.1
ReputeBad
Geno Mag Summary
(A;A) 1.1 possible increased risk for ANCA associated vasculitis
(C;C) 0 normal

Homozygous Variant of SNP upstream of SERPINA1 which may cause alpha-1-antitrypsin reduction / deficiency, also associated with granulomatosis with polyangiitis, an ANCA-associated vasculitis which can damage the kidneys and lungs. [PMID 26034600] [PMID 25452756] [PMID 22808956]

NC_000014.8:g.94863636C>A NC_000014.9:g.94397299C>A