Have questions? Visit https://www.reddit.com/r/SNPedia

rs717620

From SNPedia

Orientationminus
Stabilizedminus
Make rs717620(A;A)
Make rs717620(A;G)
Make rs717620(G;G)
ReferenceGRCh38.p2 38.2/146
Chromosome10
Position99782821
GeneABCC2
is asnp
is mentioned by
dbSNPrs717620
ebirs717620
HLIrs717620
Exacrs717620
Varsomers717620
Maprs717620
PheGenIrs717620
hapmaprs717620
1000 genomesrs717620
hgdprs717620
ensemblrs717620
gopubmedrs717620
geneviewrs717620
scholarrs717620
googlers717620
pharmgkbrs717620
gwascentralrs717620
openSNPrs717620
23andMers717620
23andMe allrs717620
SNP Nexus

SNPshotrs717620
SNPdbers717620
MSV3drs717620
GWAS Ctlgrs717620
GMAF0.1763
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 21451505OA-icon.png] Effect of ABCC2 (MRP2) Transport Function on Erythromycin Metabolism


[PMID 22630058] ABCC2 Polymorphisms and Haplotype are Associated with Drug Resistance in Chinese Epileptic Patients

[PMID 17997497] Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy.

[PMID 18926681] Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease.

[PMID 19568750OA-icon.png] MRP2 and GSTP1 polymorphisms and chemotherapy response in advanced non-small cell lung cancer.

[PMID 20061166] Genetic polymorphisms influence mycophenolate mofetil-related adverse events in pediatric heart transplant patients.

[PMID 20139798] ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir.

[PMID 22318656OA-icon.png] Interindividual variability in hepatic expression of the multidrug resistance-associated protein 2 (MRP2/ABCC2): quantification by liquid chromatography/tandem mass spectrometry.

[PMID 22473764] A comprehensive study of polymorphisms in ABCB1, ABCC2 and ABCG2 and lung cancer chemotherapy response and prognosis.


GET Evidence
rs717620
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.149935
summary



[PMID 23506516] A systematic review and meta-analysis of the role of ABCC2 variants on drug response in patients with epilepsy


[PMID 22868256OA-icon.png] A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen.


[PMID 23069858] Impact of ABCC2 polymorphisms on high-dose methotrexate pharmacokinetics in patients with lymphoid malignancy.


[PMID 24782687OA-icon.png] Multi-institutional Study of Outcomes After Pediatric Heart Transplantation: Candidate Gene Polymorphism Analysis of ABCC2


[PMID 25007187] Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia


[PMID 26107220] Quantitative Assessment of the Association between ABC Polymorphisms and Osteosarcoma Response: a Meta-analysis


[PMID 26189305] ABCB1, ABCC2, SCN1A, SCN2A, GABRA1 gene polymorphisms and drug resistant epilepsy in the Chinese Han population


[PMID 26807589] A Single-Nucleotide Polymorphism in ABCC4 Is Associated with Tenofovir-Related Beta2-Microglobulinuria in Thai Patients with HIV-1 Infection.


[PMID 27566582] Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma.