|(G;T)||1.7||1.7x increased risk for developing a peanut allergy|
|(T;T)||3||3x higher risk for developing a peanut allergy|
rs7192, also known as Leu242Val or L242V, is a SNP in the HLA-DRA gene on chromosome 6.
A study of several thousand children and their parents, most with food allergies, concluded that two SNPs, rs7192 and rs9275596, are associated with increased susceptibility to developing a peanut allergy in populations of European ancestry. The odds ratio reported for rs7192(T) were 1.7 (p=10e-8).[PMID 25710614]Detecting significant single-nucleotide polymorphisms in a rheumatoid arthritis study using random forests[PMID 20018063]
[PMID 20587610] Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection
|Title||A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia.|
|Odds Ratio||1.2900 None|
[PMID 18204098] Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
[PMID 19143810] Haplotype-based search for SNPs associated with differential type 1 diabetes risk among chromosomes carrying a specific HLA DRB1-DQA1-DQB1 haplotype.
[PMID 20018067] A two-stage search strategy for detecting multiple loci associated with rheumatoid arthritis.
[PMID 20018081] Assessment of gene-covariate interactions by incorporating covariates into association mapping.
[PMID 22201026] Genome-wide pathway analysis of a genome-wide association study on psoriasis and Behcet's disease.
|qualified_impact||Insufficiently evaluated not reviewed|
[PMID 23200760] Pathway analysis of genome-wide association study on asthma
[PMID 23053960] Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis.
[PMID 23238918] Genome-wide pathway analysis of a genome-wide association study on multiple sclerosis.