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rs719725

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.46x increased risk for colorectal cancer
(A;C) 1.5x increased risk for colorectal cancer
(C;C) 0 normal
ReferenceGRCh37 37.1/131
Chromosome9
Position6365683
is asnp
is mentioned by
dbSNPrs719725
ebirs719725
HLIrs719725
Exacrs719725
Varsomers719725
Maprs719725
PheGenIrs719725
hapmaprs719725
1000 genomesrs719725
hgdprs719725
ensemblrs719725
gopubmedrs719725
geneviewrs719725
scholarrs719725
googlers719725
pharmgkbrs719725
gwascentralrs719725
openSNPrs719725
23andMers719725
23andMe allrs719725
SNP Nexus

SNPshotrs719725
SNPdbers719725
MSV3drs719725
GWAS Ctlgrs719725
GMAF0.3255
Max Magnitude0
? (A;A) (A;C) (C;C) 28
rs719725 is a SNP on chromosome 9p24 that has been associated with increased risk of colorectal cancer, based on a study of 1,567 sibships from the Colon Cancer Family Registry.

By genotypes, the observed risks were as follows: (A;A) versus (C;C): odds ratios, 1.46, CI: 1.06-2.02; (A;C) versus (C;C): odds ratio 1.50, CI: 1.14-1.98; p = 0.011)[PMID 18056436]


[PMID 20978172OA-icon.png] Characterization of 9p24 risk locus and colorectal adenoma and cancer: gene-environment interaction and meta-analysis : gave an overall meta-analysis (n=17) OR of 1.07 (95% CI 1.03-1.12, p-trend 0.001).

[PMID 21102338OA-icon.png] Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer

[PMID 21119214OA-icon.png] Colorectal Cancer Susceptibility Loci in a Population-Based Study: Associations with Morphological Parameters


[PMID 21952639OA-icon.png] NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor


[PMID 19155440OA-icon.png] Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21.


[PMID 20648012OA-icon.png] Association studies on 11 published colorectal cancer risk loci.


[PMID 21071539OA-icon.png] Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations.


[PMID 23359760OA-icon.png] Single-nucleotide polymorphism associations for colorectal cancer in southern chinese population


[PMID 22848671OA-icon.png] Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.


[PMID 23434150OA-icon.png] Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?


[PMID 27769063] Risk of eighteen genome-wide association study-identified genetic variants for colorectal cancer and colorectal adenoma in Han Chinese.