|| common in clinvar
|| likely to be an unaffected carrier for a trimethylaminuria allele
|| trimethylaminuria & possible related issues; see discussion
, also known as Pro153Leu, is a SNP in the FMO3
gene. Homozygous minor genotypes for this SNP have been reported to have trimethylaminuria
[PMID 9398858] Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome.
[PMID 9536088] Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.
[PMID 11191884] Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FM03) gene in patients with fish-odour syndrome.