|| one CYP2D6*20 allele; lowered metabolism of certain drugs
|| Two CYP2D6*20 alleles; significantly lowered metabolism of certain drugs
rs72549354 represents a rare variation in CYP2D6 gene that is characteristic of the CYP2D6*20 allele.[PMID 10471072]
In dbSNP, the common (major) allele is represented by (-), and the rare variant allele introducing a single inserted nucleotide is represented as (C).
This variant appears to be renamed as i4001479 by 23andMe; assuming this is correct, the common allele for this variant as shown in 23andMe raw data will be (D), and the rare variant allele will be (I).