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rs72558189

From SNPedia

Warfarin (Coumadin®)
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2.5 CYP2C9*14 homozygote
(A;G) carrier of one CYP2C9*14 allele
(G;G) 0 normal
ReferenceGRCh38 38.1/141
Chromosome10
Position94942234
GeneCYP2C9
is asnp
is mentioned by
dbSNPrs72558189
ebirs72558189
HLIrs72558189
Exacrs72558189
Varsomers72558189
Maprs72558189
PheGenIrs72558189
hapmaprs72558189
1000 genomesrs72558189
hgdprs72558189
ensemblrs72558189
gopubmedrs72558189
geneviewrs72558189
scholarrs72558189
googlers72558189
pharmgkbrs72558189
gwascentralrs72558189
openSNPrs72558189
23andMers72558189
23andMe allrs72558189
SNP Nexus

SNPshotrs72558189
SNPdbers72558189
MSV3drs72558189
GWAS Ctlgrs72558189
Max Magnitude2.5
CPMC Logo.png

This SNP has been recognized by the Coriell Personalized Medicine Collaborative ICOB.
Additional information is available here

rs72558189, also known as 374G>A, 3552G>A or R125H, is a SNP in the CYP2C9 gene.

The rs72558189(A) allele defines the CYP2C9*14 variant, which may have decreased activity.

ClinVar
Risk rs72558189(A;A)
Alt rs72558189(A;A)
Reference rs72558189(G;G)
Significance Untested
Disease
Variation info
Gene CYP2C9
CLNDBN
Reversed 0
HGVS NC_000010.10:g.96701991G>A
CLNSRC
CLNACC


[PMID 15371982] Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose.


[PMID 16099926] Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.