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rs7294

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs7294(A;A)
Make rs7294(A;G)
ReferenceGRCh38 38.1/141
Chromosome16
Position31091000
GeneVKORC1
is asnp
is mentioned by
dbSNPrs7294
ebirs7294
HLIrs7294
Exacrs7294
Varsomers7294
Maprs7294
PheGenIrs7294
hapmaprs7294
1000 genomesrs7294
hgdprs7294
ensemblrs7294
gopubmedrs7294
geneviewrs7294
scholarrs7294
googlers7294
pharmgkbrs7294
gwascentralrs7294
openSNPrs7294
23andMers7294
23andMe allrs7294
SNP Nexus

SNPshotrs7294
SNPdbers7294
MSV3drs7294
GWAS Ctlgrs7294
Merged fromRs17880624
GMAF0.3108
Max Magnitude0
? (A;A) (A;G) (G;G) 28
[PMID 19436136OA-icon.png] Association of sequence variations in vitamin K epoxide reductase and gamma-glutamyl carboxylase genes with biochemical measures of vitamin K status



[PMID 21127708OA-icon.png] Genetic Variation of VKORC1 and CYP4F2 Genes Related to Warfarin Maintenance Dose in Patients with Myocardial Infarction


[PMID 21590310] Evaluation of the effects of VKORC1 polymorphisms and haplotypes, CYP2C9 genotypes, and clinical factors on warfarin response in Sudanese patients


[PMID 17048007OA-icon.png] Association of warfarin dose with genes involved in its action and metabolism.


[PMID 18252229OA-icon.png] Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.


[PMID 18305455OA-icon.png] Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin.


[PMID 18466099OA-icon.png] Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans.


[PMID 18523153OA-icon.png] Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement.


[PMID 18535201OA-icon.png] A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.


[PMID 18698231OA-icon.png] Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.


[PMID 18752379OA-icon.png] Warfarin pharmacogenetics.


[PMID 18855533OA-icon.png] VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.


[PMID 19226183OA-icon.png] Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient.


[PMID 19228618OA-icon.png] Estimation of the warfarin dose with clinical and pharmacogenetic data.


[PMID 19955245OA-icon.png] Warfarin sensitivity genotyping: a review of the literature and summary of patient experience.


[PMID 20018050OA-icon.png] Application of sex-specific single-nucleotide polymorphism filters in genome-wide association data.


[PMID 21359226OA-icon.png] The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected.


[PMID 23208322] Influence of ORM1 polymorphisms on the maintenance stable warfarin dosage


[PMID 23662025OA-icon.png] Genetic variation and haplotype structure of the gene Vitamin K epoxide reductase complex, subunit 1 in the Tamilian population


[PMID 23133420OA-icon.png] Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin.


ClinVar
Risk rs7294(A;A)
Alt rs7294(A;A)
Reference rs7294(G;G)
Significance Drug-response
Disease phenprocoumon response - Dosage warfarin response - Dosage acenocoumarol response - Dosage
Variation info
Gene VKORC1
CLNDBN phenprocoumon response - Dosage warfarin response - Dosage acenocoumarol response - Dosage
Reversed 1
HGVS NC_000016.9:g.31102321C>T
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211189.1, RCV000211278.1, RCV000211362.1,