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rs7297610

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in clinvar
Make rs7297610(C;T)
Make rs7297610(T;T)
ReferenceGRCh38 38.1/141
Chromosome12
Position69430244
is asnp
is mentioned by
dbSNPrs7297610
ebirs7297610
HLIrs7297610
Exacrs7297610
Varsomers7297610
Maprs7297610
PheGenIrs7297610
hapmaprs7297610
1000 genomesrs7297610
hgdprs7297610
ensemblrs7297610
gopubmedrs7297610
geneviewrs7297610
scholarrs7297610
googlers7297610
pharmgkbrs7297610
gwascentralrs7297610
openSNPrs7297610
23andMers7297610
23andMe allrs7297610
SNP Nexus

SNPshotrs7297610
SNPdbers7297610
MSV3drs7297610
GWAS Ctlgrs7297610
GMAF0.1061
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS
SNP rs317689,rs315135,rs7297610
PubMedID [PMID 18591461OA-icon.png]
Condition Response to diuretic therapy
Gene LYZ, YEATS4, FRS2
Risk Allele e
pValue 6.00E-006
OR NA
95% CI



[PMID 22350108OA-icon.png] Association of chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression.


GET Evidence
rs7297610
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.166667
summary



ClinVar
Risk rs7297610(T;T)
Alt rs7297610(T;T)
Reference rs7297610(C;C)
Significance Drug-response
Disease hydrochlorothiazide response - Efficacy
Variation info
Gene
CLNDBN hydrochlorothiazide response - Efficacy
Reversed 0
HGVS NC_000012.11:g.69824024C>T
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211271.1,