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rs730012

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common in clinvar
Make rs730012(A;C)
Make rs730012(C;C)
ReferenceGRCh38 38.1/141
Chromosome5
Position179793637
GeneLOC100289556, LTC4S
is asnp
is mentioned by
dbSNPrs730012
ebirs730012
HLIrs730012
Exacrs730012
Varsomers730012
Maprs730012
PheGenIrs730012
hapmaprs730012
1000 genomesrs730012
hgdprs730012
ensemblrs730012
gopubmedrs730012
geneviewrs730012
scholarrs730012
googlers730012
pharmgkbrs730012
gwascentralrs730012
openSNPrs730012
23andMers730012
23andMe allrs730012
SNP Nexus

SNPshotrs730012
SNPdbers730012
MSV3drs730012
GWAS Ctlgrs730012
GMAF0.1993
Max Magnitude0
? (A;A) (A;C) (C;C) 28
[PMID 15726497OA-icon.png] Gene-environment interaction effects on the development of immune responses in the 1st year of life.


[PMID 18366797OA-icon.png] Influence of leukotriene gene polymorphisms on chronic rhinosinusitis.


[PMID 19131662OA-icon.png] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.


[PMID 19214143OA-icon.png] 5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci.


[PMID 19223558OA-icon.png] Polymorphic variation in NFKB1 and other aspirin-related genes and risk of Hodgkin lymphoma.


[PMID 19263529OA-icon.png] Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.


[PMID 19330901OA-icon.png] Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.


[PMID 19559392OA-icon.png] A candidate gene association study of 77 polymorphisms in migraine.


[PMID 19665766OA-icon.png] Genetics and pharmacogenetics of the leukotriene pathway.


[PMID 20031584OA-icon.png] Genetics of atherothrombotic and lacunar stroke.


[PMID 20592916OA-icon.png] Pharmacogenomic approaches to asthma treatment.


[PMID 23079278] Genetic variation in members of the leukotrienes biosynthesis pathway confers risk of ischemic stroke in Eastern Han Chinese


GET Evidence
rs730012
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.195312
summary



[PMID 23663310OA-icon.png] Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.


ClinVar
Risk rs730012(C;C)
Alt rs730012(C;C)
Reference rs730012(A;A)
Significance Drug-response
Disease aspirin response - Toxicity/ADR
Variation info
Gene LTC4S
CLNDBN aspirin response - Toxicity/ADR
Reversed 0
HGVS NC_000005.9:g.179220638A>C
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211358.1,