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rs7301328

From SNPedia

Orientationplus
Stabilizedplus
Make rs7301328(C;C)
Make rs7301328(C;G)
Make rs7301328(G;G)
ReferenceGRCh38 38.1/141
Chromosome12
Position13865843
GeneGRIN2B
is asnp
is mentioned by
dbSNPrs7301328
ebirs7301328
HLIrs7301328
Exacrs7301328
Varsomers7301328
Maprs7301328
PheGenIrs7301328
hapmaprs7301328
1000 genomesrs7301328
hgdprs7301328
ensemblrs7301328
gopubmedrs7301328
geneviewrs7301328
scholarrs7301328
googlers7301328
pharmgkbrs7301328
gwascentralrs7301328
openSNPrs7301328
23andMers7301328
23andMe allrs7301328
SNP Nexus

SNPshotrs7301328
SNPdbers7301328
MSV3drs7301328
GWAS Ctlgrs7301328
GMAF0.4036
Max Magnitude
? (C;C) (C;G) (G;G) 28
rs7301328 ( 366C/G / Pro122Pro ) is a SNP within GRIN2B (Glutamate [NMDA] receptor subunit epsilon-2).

[PMID 19562769] small study (consisting of 404 Parkinson's patients) found association of the CC genotype with increased incidence of impulsive control and related behaviors

no assoc. noted with
[PMID 19605943] lithium response and [PMID 19005876] bipolar disorder with any GRIN2B SNPs tested (366G/C, -200G/T and rs890)
[PMID 15542698] alcoholism
[PMID 12824739] treatment-refractory schizophrenia - 'not a major risk factor', higher mean clozapine dosage noted with the rs1806201(C;C) genotype


[PMID 19911060OA-icon.png] Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.


[PMID 20537720] Positive association between GRIN2B gene and bipolar disorder in the Chinese Han Population.


[PMID 24114429] A study of N-methyl-D-aspartate receptor gene (GRIN2B) variants as predictors of treatment-resistant major depression


[PMID 23408766OA-icon.png] Assessment of NMDA receptor genes (GRIN2A, GRIN2B and GRIN2C) as candidate genes in the development of degenerative lumbar scoliosis.


ClinVar
Risk rs7301328(C;C)
Alt rs7301328(C;C)
Reference rs7301328(G;G)
Significance Other
Disease not specified
Variation info
Gene GRIN2B
CLNDBN not specified
Reversed 0
HGVS NC_000012.11:g.14018777G>C
CLNSRC ClinVar GeneDx University of Chicago
CLNACC RCV000117198.3,