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rs735396

From SNPedia

Orientationminus
Stabilizedminus
Make rs735396(A;A)
Make rs735396(A;G)
Make rs735396(G;G)
ReferenceGRCh38 38.1/141
Chromosome12
Position121001041
GeneHNF1A
is asnp
is mentioned by
dbSNPrs735396
ebirs735396
HLIrs735396
Exacrs735396
Varsomers735396
Maprs735396
PheGenIrs735396
hapmaprs735396
1000 genomesrs735396
hgdprs735396
ensemblrs735396
gopubmedrs735396
geneviewrs735396
scholarrs735396
googlers735396
pharmgkbrs735396
gwascentralrs735396
openSNPrs735396
23andMers735396
23andMe allrs735396
SNP Nexus

SNPshotrs735396
SNPdbers735396
MSV3drs735396
GWAS Ctlgrs735396
GMAF0.3673
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 21203500OA-icon.png]
Trait
Title Genomics Meets Glycomics-The First GWAS Study of Human N-Glycome Identifies HNF1± as a Master Regulator of Plasma Protein Fucosylation
Risk Allele G
P-val 4E-8
Odds Ratio 0.1700 [0.11-0.23] unit increase

[PMID 18439548OA-icon.png] Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

[PMID 19672314OA-icon.png] Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes.


GET Evidence
rs735396
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.290296
summary