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rs7385804

From SNPedia

Orientationplus
Stabilizedplus
Make rs7385804(A;A)
Make rs7385804(A;C)
Make rs7385804(C;C)
ReferenceGRCh38 38.1/141
Chromosome7
Position100638347
GeneTFR2
is asnp
is mentioned by
dbSNPrs7385804
ebirs7385804
HLIrs7385804
Exacrs7385804
Varsomers7385804
Maprs7385804
PheGenIrs7385804
hapmaprs7385804
1000 genomesrs7385804
hgdprs7385804
ensemblrs7385804
gopubmedrs7385804
geneviewrs7385804
scholarrs7385804
googlers7385804
pharmgkbrs7385804
gwascentralrs7385804
openSNPrs7385804
23andMers7385804
23andMe allrs7385804
SNP Nexus

SNPshotrs7385804
SNPdbers7385804
MSV3drs7385804
GWAS Ctlgrs7385804
GMAF0.3131
Max Magnitude
? (A;A) (A;C) (C;C) 28
GWAS snp
PMID [PMID 19820697OA-icon.png]
Trait Hematological parameters
Title A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
Risk Allele C
P-val 5E-10
Odds Ratio 0.01 [0.004-0.008] 10^12/l increase
GWAS snp
PMID [PMID 19862010OA-icon.png]
Trait Hematocrit
Title Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
Risk Allele C
P-val 4E-10
Odds Ratio 0.15 [0.10-0.20] % decrease
GWAS snp
PMID [PMID 21208937OA-icon.png]
Trait
Title Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels
Risk Allele A
P-val 7E-8
Odds Ratio 3.2300 [2.05-4.41] ug/dl increase

[PMID 22323359] TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia.


GET Evidence
rs7385804
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.65873
summary



[PMID 23751596] Association between genetic variations in TFR2 gene and coronary heart disease in Chinese: a case-control study