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rs738722

From SNPedia

Orientationplus
Stabilizedplus
Make rs738722(C;C)
Make rs738722(C;T)
Make rs738722(T;T)
ReferenceGRCh38 38.1/141
Chromosome22
Position28734024
GeneCHEK2
is asnp
is mentioned by
dbSNPrs738722
ebirs738722
HLIrs738722
Exacrs738722
Varsomers738722
Maprs738722
PheGenIrs738722
hapmaprs738722
1000 genomesrs738722
hgdprs738722
ensemblrs738722
gopubmedrs738722
geneviewrs738722
scholarrs738722
googlers738722
pharmgkbrs738722
gwascentralrs738722
openSNPrs738722
23andMers738722
23andMe allrs738722
SNP Nexus

SNPshotrs738722
SNPdbers738722
MSV3drs738722
GWAS Ctlgrs738722
GMAF0.32
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 20729852OA-icon.png]
Trait
Title A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
Risk Allele T
P-val 1E-8
Odds Ratio 1.30 [1.19-1.43]


[PMID 22201027] Variant allele of CHEK2 is associated with a decreased risk of esophageal cancer lymph node metastasis in a Chinese population


[PMID 21553226] Increased risk of advanced prostate cancer associated with MnSOD Ala-9-Val gene polymorphism.


[PMID 17132159OA-icon.png] Comprehensive analysis of the ATM, CHEK2 and ERBB2 genes in relation to breast tumour characteristics and survival: a population-based case-control and follow-up study.


[PMID 17428325OA-icon.png] Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.


[PMID 25008389OA-icon.png] HPV seropositivity joints with susceptibility loci identified in GWASs at apoptosis associated genes to increase the risk of Esophageal Squamous Cell Carcinoma (ESCC)