rs74315403(A;G)
From SNPedia
| PrP D178N pathogenic mutation - leads to CJD or FFI |
| Is a | genotype |
| of | rs74315403 |
| Gene | PRNP |
| Chromosome | 20 |
| Position | 4,699,752 |
| mentioned | by |
| Magnitude | 6.5 |
| Repute | Bad |
| Geno | Mag | Summary |
|---|---|---|
| (A;G) | 6.5 | PrP D178N pathogenic mutation - leads to CJD or FFI |
| (G;G) | 0 | PrP codon 178 (D) - non pathogenic variant |
This SNP creates a D178N mutation within the Prion Protein, which leads to inherited Creutzfeldt-Jakob disease or Fatal Familial Insomnia.
