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rs743572

From SNPedia

Orientationplus
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Make rs743572(A;A)
Make rs743572(A;G)
Make rs743572(G;G)
ReferenceGRCh38 38.1/142
Chromosome10
Position102837395
GeneCYP17A1
is asnp
is mentioned by
dbSNPrs743572
ebirs743572
HLIrs743572
Exacrs743572
Varsomers743572
Maprs743572
PheGenIrs743572
hapmaprs743572
1000 genomesrs743572
hgdprs743572
ensemblrs743572
gopubmedrs743572
geneviewrs743572
scholarrs743572
googlers743572
pharmgkbrs743572
gwascentralrs743572
openSNPrs743572
23andMers743572
23andMe allrs743572
SNP Nexus

SNPshotrs743572
SNPdbers743572
MSV3drs743572
GWAS Ctlgrs743572
GMAF0.4201
Max Magnitude

rs743572, known best as the CYP17 -34 T/C or T>C variant, is a variant in the 5' upstream region of the CYP17A1 gene.

? (A;A) (A;G) (G;G) 28

[PMID 19415745] Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women


[PMID 18682255] Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions


[PMID 20432167] Dietary isoflavone intake, polymorphisms in the CYP17, CYP19, 17beta-HSD1, and SHBG genes, and risk of breast cancer in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians


[PMID 21824047] Genetic polymorphisms associated with steroids metabolism and insulin action in polycystic ovary syndrome


[PMID 22418777OA-icon.png] Estrogen-related genes and their contribution to racial differences in breast cancer risk


[PMID 22658813] Association Between Polymorphisms in COMT, PLCH1, and CYP17A1, and Non-Small-Cell Lung Cancer Risk in Chinese Nonsmokers

[PMID 17307805] CYP17 genotype is associated with short menstrual cycles, early oral contraceptive use and BRCA mutation status in young healthy women.

[PMID 17615053OA-icon.png] Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk.

[PMID 17986287] The rs743572 common variant in the promoter of CYP17A1 is not associated with prostate cancer risk or circulating hormonal levels.

[PMID 18006912] CYP17 genetic variation and risk of breast and prostate cancer from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).

[PMID 18163429OA-icon.png] Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study.

[PMID 18172694] Genetic variation in CYP17 and endometrial cancer risk.

[PMID 18437511OA-icon.png] Variants in hormone biosynthesis genes and risk of endometrial cancer.

[PMID 18483327OA-icon.png] Polymorphisms in steroid hormone biosynthesis genes and risk of breast cancer and fibrocystic breast conditions in Chinese women.

[PMID 18601603] Polymorphisms of CYP17A1, CYP19, and androgen in Brazilian women with uterine leiomyomas.

[PMID 18603647OA-icon.png] Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.

[PMID 18628428OA-icon.png] Polymorphisms in genes involved in sex hormone metabolism, estrogen plus progestin hormone therapy use, and risk of postmenopausal breast cancer.

[PMID 18629629] Association of genetic polymorphisms of ER-alpha and the estradiol-synthesizing enzyme genes CYP17 and CYP19 with breast cancer risk in Chinese women.

[PMID 18805939OA-icon.png] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.

[PMID 19015200OA-icon.png] Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.

[PMID 19127255OA-icon.png] Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium.

[PMID 19174490OA-icon.png] Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women.

[PMID 19387820OA-icon.png] Genetic polymorphisms of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes in adolescent girls with polycystic ovary syndrome.

[PMID 19679043OA-icon.png] African American-preponderant single nucleotide polymorphisms (SNPs) and risk of breast cancer.

[PMID 20171624] Solitary and multiple uterine leiomyomas among Caucasian women: two different disorders?

[PMID 20411041OA-icon.png] Common Variation in the CYP17A1 and IFIT1 Genes on Chromosome 10 Does Not Contribute to the Risk of Endometriosis.

[PMID 20798986] The CYP17A1 -34T > C polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers.

[PMID 21229561] CYP17 gene polymorphisms and prostate cancer risk: A meta-analysis based on 38 independent studies.

[PMID 21644229] [Association of single nucleotide polymorphism in CYP17 and ERalpha genes with endometriosis risk in southern Chinese women].

[PMID 21656827] CYP17 gene polymorphisms and prostate cancer risk: a meta-analysis based on 38 independent studies.


[PMID 23129512OA-icon.png] Polymorphisms in CYP17 and CYP3A4 and prostate cancer in men of African descent


[PMID 24430361] Genetic polymorphisms of ESR1, ESR2, CYP17A1, and CYP19A1 and the risk of breast cancer: a case control study from North India


[PMID 22714708] Genetic polymorphisms of CYP17A1 in steroidogenesis pathway are associated with risk of progression to castration-resistant prostate cancer in Japanese men receiving androgen deprivation therapy.


[PMID 23649771] Genetic variation of the CYP17 and susceptibility to endometrial cancer: a meta-analysis.


[PMID 23809139] Polymorphic variants of CYP17 and CYP19A and risk of infertility in endometriosis.


[PMID 25323563] Quantitative Assessment of the Association Between CYP17 rs743572 Polymorphism and Prostate Cancer Risk


[PMID 26263970OA-icon.png] A Single Nucleotide Polymorphism near the CYP17A1 Gene Is Associated with Left Ventricular Mass in Hypertensive Patients under Pharmacotherapy


[PMID 26276290] Relationship between gene polymorphisms and prostate cancer risk


[PMID 26407154] Evaluation of CYP17A1 and LEP Gene Polymorphisms in Breast Cancer


[PMID 26940238] Association between CYP17A1 rs3824755 and rs743572 gene polymorphisms and Alzheimer's disease in the Chinese Han population.