Have questions? Visit https://www.reddit.com/r/SNPedia

rs748404

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
(C;T) 1.15 very slightly increased risk (1.15) for lung cancer
(T;T) 1.25 slightly increased risk (1.25) for lung cancer
ReferenceGRCh38 38.1/141
Chromosome15
Position43267033
GeneTGM5
is asnp
is mentioned by
dbSNPrs748404
ebirs748404
HLIrs748404
Exacrs748404
Varsomers748404
Maprs748404
PheGenIrs748404
hapmaprs748404
1000 genomesrs748404
hgdprs748404
ensemblrs748404
gopubmedrs748404
geneviewrs748404
scholarrs748404
googlers748404
pharmgkbrs748404
gwascentralrs748404
openSNPrs748404
23andMers748404
23andMe allrs748404
SNP Nexus

SNPshotrs748404
SNPdbers748404
MSV3drs748404
GWAS Ctlgrs748404
GMAF0.1524
Max Magnitude1.25
? (C;C) (C;T) (T;T) 28

In a GWAS dataset of 1,447 lung cancer cases, and then replicated in another 1300 cases, the rs748404(T) allele was significantly correlated with increased risk (odds ratio 1.15, p = 1.1 × 10e-9), in agreement with a previous meta-analysis.[PMID 21303977OA-icon.png]


[PMID 19654303OA-icon.png] Deciphering the Impact of Common Genetic Variation on Lung Cancer Risk: A Genome-Wide Association Study


GET Evidence
rs748404
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.171875
summary