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rs7538490

From SNPedia

Orientationplus
Stabilizedplus
Make rs7538490(C;C)
Make rs7538490(C;T)
Make rs7538490(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position162121540
GeneNOS1AP
is asnp
is mentioned by
dbSNPrs7538490
ebirs7538490
HLIrs7538490
Exacrs7538490
Varsomers7538490
Maprs7538490
PheGenIrs7538490
hapmaprs7538490
1000 genomesrs7538490
hgdprs7538490
ensemblrs7538490
gopubmedrs7538490
geneviewrs7538490
scholarrs7538490
googlers7538490
pharmgkbrs7538490
gwascentralrs7538490
openSNPrs7538490
23andMers7538490
23andMe allrs7538490
SNP Nexus

SNPshotrs7538490
SNPdbers7538490
MSV3drs7538490
GWAS Ctlgrs7538490
GMAF0.3343
Max Magnitude
? (C;C) (C;T) (T;T) 28

The T-allele of NOS1AP rs3020781 was previously reported to be strongly associated with type-2 diabetes in various European-descent populations comprising a total of 2,198 individuals with a combined odds ratio (OR) of 1.53 [1.28-1.81].

However, in a combined study sample comprising a total of 16,801 and 16,913 individuals from Denmark, no significant association was found to diabetes or obesity.[PMID 19111066OA-icon.png]


[PMID 19389826OA-icon.png] Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q