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rs7561317

From SNPedia

Orientationplus
Stabilizedplus
Make rs7561317(A;A)
Make rs7561317(A;G)
Make rs7561317(G;G)
ReferenceGRCh37 37.1/131
Chromosome2
Position644953
is asnp
is mentioned by
dbSNPrs7561317
ebirs7561317
HLIrs7561317
Exacrs7561317
Varsomers7561317
Maprs7561317
PheGenIrs7561317
hapmaprs7561317
1000 genomesrs7561317
hgdprs7561317
ensemblrs7561317
gopubmedrs7561317
geneviewrs7561317
scholarrs7561317
googlers7561317
pharmgkbrs7561317
gwascentralrs7561317
openSNPrs7561317
23andMers7561317
23andMe allrs7561317
SNP Nexus

SNPshotrs7561317
SNPdbers7561317
MSV3drs7561317
GWAS Ctlgrs7561317
GMAF0.1667
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19079260]
Trait Body mass index
Title Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
Risk Allele G
P-val 4E-17
Odds Ratio 6.12 [4.69-7.55] % SD


[PMID 19851340] Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population




[PMID 21625854] Implication of genetic variants near TMEM18, BCDIN3D/FAIM2, and MC4R with coronary artery disease and obesity in Chinese: a angiography-based study


[PMID 21912638OA-icon.png] Studies of metabolic phenotypic correlates of 15 obesity associated gene variants

[PMID 19478790OA-icon.png] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.

[PMID 20127379OA-icon.png] From monogenic to polygenic obesity: recent advances.

[PMID 20380707OA-icon.png] The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children.

[PMID 20712903OA-icon.png] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.

[PMID 24670271] Association study of common polymorphisms in MSRA, TFAP2B, MC4R, NRXN3, PPARGC1A, TMEM18, SEC16B, HOXB5 and OLFM4 genes with obesity-related traits among Portuguese children.


GET Evidence
rs7561317
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.84375
summary



[PMID 23860325] Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes


[PMID 24348519OA-icon.png] EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children