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rs7568369

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) normal
(G;T) 1.1 0.90x reduced risk of obesity
(T;T) 1.1 0.90x reduced risk of obesity
ReferenceGRCh38 38.1/141
Chromosome2
Position207166591
GeneKLF7, MIR7845
is asnp
is mentioned by
dbSNPrs7568369
ebirs7568369
HLIrs7568369
Exacrs7568369
Varsomers7568369
Maprs7568369
PheGenIrs7568369
hapmaprs7568369
1000 genomesrs7568369
hgdprs7568369
ensemblrs7568369
gopubmedrs7568369
geneviewrs7568369
scholarrs7568369
googlers7568369
pharmgkbrs7568369
gwascentralrs7568369
openSNPrs7568369
23andMers7568369
23andMe allrs7568369
SNP Nexus

SNPshotrs7568369
SNPdbers7568369
MSV3drs7568369
GWAS Ctlgrs7568369
GMAF0.3122
Max Magnitude1.1
? (G;G) (G;T) (T;T) 28
rs7568369, also known as -963C>A, is a SNP in the Kruppel-like factor 7 KLF7 gene.

A study of 14,818 Danish individuals with obesity found that the rs7568369(T) allele reduced obesity risk (odds ratio 0.90, CI: 0.84-0.96, p=0.001) and in studies of quantitative traits (n=5,535), this allele was associated with decreased body mass index (p=0.002) and waist circumference (p=0.003).[PMID 19147600]