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rs7569963

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0
Make rs7569963(A;A)
Make rs7569963(A;G)
ReferenceGRCh38 38.1/141
Chromosome2
Position207608460
GeneFAM119A
is asnp
is mentioned by
dbSNPrs7569963
ebirs7569963
HLIrs7569963
Exacrs7569963
Varsomers7569963
Maprs7569963
PheGenIrs7569963
hapmaprs7569963
1000 genomesrs7569963
hgdprs7569963
ensemblrs7569963
gopubmedrs7569963
geneviewrs7569963
scholarrs7569963
googlers7569963
pharmgkbrs7569963
gwascentralrs7569963
openSNPrs7569963
23andMers7569963
23andMe allrs7569963
SNP Nexus

SNPshotrs7569963
SNPdbers7569963
MSV3drs7569963
GWAS Ctlgrs7569963
GMAF0.1809
Max Magnitude0
? (A;A) (A;G) (G;G) 28
rs7569963 is directly adjacent to CREB1.

[PMID 17548750] Associated with significantly (p = 0.005) increased chance of suicide in a study of 1447 citalopram users (male only subgroup, 539 in total). Two haplotypes (see below) also showed significant association with suicidality in the male subgroup.



[PMID 20643483] A preliminary investigation of the influence of CREB1 gene on treatment resistance in major depression.


GET Evidence
rs7569963
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.234375
summary