|| common in clinvar
|?|| (G;G) (G;T) (T;T) ||28|
| Disease Association
|| Defects in ABCC8 may contribute to non-insulin-dependent diabetes mellitus (NIDDM), also known as type II diabetes mellitus, in Northern European Caucasians.
] Polymorphism in maternal LRP8 gene is associated with fetal growth.
[PMID 17903298] Genome-wide association with diabetes-related traits in the Framingham Heart Study.
[PMID 18599530] Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.
[PMID 19641380] Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans.
|| not reviewed
|| Insufficiently evaluated not reviewed