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rs7594645

From SNPedia

Associated with memory performance in older adults.
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0
(A;G) 2 very slightly better memory performance in older adults
(G;G) 2.1 slightly better memory performance in older adults
ReferenceGRCh38 38.1/142
Chromosome2
Position206781950
GeneFASTKD2, MIR3130-2
is asnp
is mentioned by
dbSNPrs7594645
ebirs7594645
HLIrs7594645
Exacrs7594645
Varsomers7594645
Maprs7594645
PheGenIrs7594645
hapmaprs7594645
1000 genomesrs7594645
hgdprs7594645
ensemblrs7594645
gopubmedrs7594645
geneviewrs7594645
scholarrs7594645
googlers7594645
pharmgkbrs7594645
gwascentralrs7594645
openSNPrs7594645
23andMers7594645
23andMe allrs7594645
SNP Nexus

SNPshotrs7594645
SNPdbers7594645
MSV3drs7594645
GWAS Ctlgrs7594645
Max Magnitude2.1
? (A;A) (A;G) (G;G) 28
In "FASTKD2 is associated with memory and hippocampal structure in older adults"[PMID 25385369] researchers in GWAS study they call the largest study of human memory to date (end of 2014) found allele G of rs7594645 associated with a "modest additive" positive effect on memory performance in older adults, together with increased hippocampal volume and gray matter density and decreased cerebrospinal fluid levels of apoptotic mediators. rs7594645 resides in FASTKD2, a gene involved in programmed cell death, suggesting a likely cause of effect.