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rs762421

From SNPedia

Orientationplus
Stabilizedplus
Make rs762421(A;A)
Make rs762421(A;G)
Make rs762421(G;G)
ReferenceGRCh38 38.1/141
Chromosome21
Position44195678
GeneC21orf33
is asnp
is mentioned by
dbSNPrs762421
ebirs762421
HLIrs762421
Exacrs762421
Varsomers762421
Maprs762421
PheGenIrs762421
hapmaprs762421
1000 genomesrs762421
hgdprs762421
ensemblrs762421
gopubmedrs762421
geneviewrs762421
scholarrs762421
googlers762421
pharmgkbrs762421
gwascentralrs762421
openSNPrs762421
23andMers762421
23andMe allrs762421
SNP Nexus

SNPshotrs762421
SNPdbers762421
MSV3drs762421
GWAS Ctlgrs762421
GMAF0.3843
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 18587394OA-icon.png]
Trait Crohn's disease
Title Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
Risk Allele G
P-val 1.0000000000000001E-9
Odds Ratio 1.13 [NR]

DeCode reports that rs762421 is associated with susceptibility to Crohn's disease. [PMID 18587394OA-icon.png]

[PMID 19068216OA-icon.png] Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.

[PMID 19557189OA-icon.png] Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

[PMID 21304977OA-icon.png] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.


GET Evidence
rs762421
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.742188
summary



[PMID 24480412] PTPN2 rs1893217 single-nucleotide polymorphism is associated with risk of Behçet's disease in a Chinese Han population