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rs766173

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 2
(T;T) 0 common in complete genomics
Make rs766173(G;T)
ReferenceGRCh38 38.1/142
Chromosome13
Position32332343
GeneBRCA2
is asnp
is mentioned by
dbSNPrs766173
ebirs766173
HLIrs766173
Exacrs766173
Varsomers766173
Maprs766173
PheGenIrs766173
hapmaprs766173
1000 genomesrs766173
hgdprs766173
ensemblrs766173
gopubmedrs766173
geneviewrs766173
scholarrs766173
googlers766173
pharmgkbrs766173
gwascentralrs766173
openSNPrs766173
23andMers766173
23andMe allrs766173
SNP Nexus

SNPshotrs766173
SNPdbers766173
MSV3drs766173
GWAS Ctlgrs766173
GMAF0.05831
Max Magnitude2
? (G;G) (G;T) (T;T) 28
This SNP, a variant in the BRCA2 gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for breast cancer. [PMID 17341484]

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for breast cancer, refer to the SNPedia breast cancer entry.

For this particular SNP, the risk (minor) allele is (G).

Neighborrs144848
Distance249


ClinVar
Risk rs766173(C,G;C,G)
Alt rs766173(C,G;C,G)
Reference rs766173(T;T)
Significance Probable-non-pathogenic
Disease not provided Breast-ovarian cancer not specified Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation info
Gene BRCA2
CLNDBN not provided Breast-ovarian cancer, familial 2 not specified Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed 1
HGVS NC_000013.10:g.32906480A>C; NC_000013.10:g.32906480A>G
CLNSRC Inc.
CLNACC RCV000034465.3, RCV000112858.4, RCV000120305.3, RCV000130996.3, RCV000031759.4, RCV000045592.3, RCV000164485.1,



[PMID 16857995OA-icon.png] Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes.


GET Evidence
BRCA2-N289H
aa_change Asn289His
aa_change_short N289H
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0290341
summary