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rs7696175

From SNPedia

Orientationplus
Stabilizedplus
Make rs7696175(C;C)
Make rs7696175(C;T)
Make rs7696175(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position38819365
is asnp
is mentioned by
dbSNPrs7696175
ebirs7696175
HLIrs7696175
Exacrs7696175
Varsomers7696175
Maprs7696175
PheGenIrs7696175
hapmaprs7696175
1000 genomesrs7696175
hgdprs7696175
ensemblrs7696175
gopubmedrs7696175
geneviewrs7696175
scholarrs7696175
googlers7696175
pharmgkbrs7696175
gwascentralrs7696175
openSNPrs7696175
23andMers7696175
23andMe allrs7696175
SNP Nexus

SNPshotrs7696175
SNPdbers7696175
MSV3drs7696175
GWAS Ctlgrs7696175
GMAF0.2608
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs7696175 in the TLR1, TLR6 loci;

Breast Cancer Risk

[PMID 22965832] For Southern Chinese: Variants of rs7696175/TLR1, TLR6, rs13281615/8q24, and rs16886165/MAP3K1 were also associated with increased breast cancer risk, with per-allele ORs (95 % CI) of 1.16 (1.00–1.34), 1.15 (1.02–1.29), and 1.15 (1.01–1.29), respectively.

[PMID 23563089OA-icon.png] For Hispanic: Three of the five significant variants (rs17157903-RELN, rs7696175-TLR1 and rs13387042-2q35) were associated with risk among Hispanics but not in Non Hispanic Whites.

References:

[PMID 22965832] Chan et al, 2012 http://link.springer.com/article/10.1007%2Fs10549-012-2234-y

[PMID 23563089OA-icon.png] Fejerman et al, 2013


[PMID 19619313OA-icon.png] An assessment of the portability of ancestry informative markers between human populations.


[PMID 19639606OA-icon.png] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.


[PMID 20200442OA-icon.png] Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.


[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.