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rs7702187

From SNPedia

Orientationplus
Stabilizedplus
Make rs7702187(A;A)
Make rs7702187(A;T)
Make rs7702187(T;T)
ReferenceGRCh38 38.1/141
Chromosome5
Position9332169
GeneSEMA5A
is asnp
is mentioned by
dbSNPrs7702187
ebirs7702187
HLIrs7702187
Exacrs7702187
Varsomers7702187
Maprs7702187
PheGenIrs7702187
hapmaprs7702187
1000 genomesrs7702187
hgdprs7702187
ensemblrs7702187
gopubmedrs7702187
geneviewrs7702187
scholarrs7702187
googlers7702187
pharmgkbrs7702187
gwascentralrs7702187
openSNPrs7702187
23andMers7702187
23andMe allrs7702187
SNP Nexus

SNPshotrs7702187
SNPdbers7702187
MSV3drs7702187
GWAS Ctlgrs7702187
GMAF0.32
Max Magnitude
? (A;A) (A;T) (T;T) 28
rs7702187 increases susceptibility to Parkinson's disease 1.74 times for carriers of the A allele [PMID 16252231OA-icon.png]

[PMID 18950607] rs7702187 had no association with the risk of developing Parkinson's disease in a study of 340 Han Chinese patients.

Neighborrs6896702
Distance433
GWAS
SNP rs7702187
PubMedID [PMID 16252231OA-icon.png]
Condition Parkinson's disease
Gene SEMA5A
Risk Allele
pValue 8.00E-006
OR 1.74
95% CI 1.36-2.24


OMIM168600
DescPARKINSON DISEASE; PD
Variant
Relatedalso



[PMID 16481103] Polymorphism in semaphorin 5A (Sema5A) gene is not a marker of Parkinson's disease risk.


[PMID 16685660OA-icon.png] Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease.


[PMID 16685661OA-icon.png] Genomewide association, Parkinson disease, and PARK10.


[PMID 16685662OA-icon.png] No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening.


[PMID 16685663OA-icon.png] A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan.


[PMID 19957501] [Correlation study of semaphorin 5a with risk of Parkinson's disease in a Chinese Han population].


GET Evidence
rs7702187
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.625
summary