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rs7743761(A;A)

From SNPedia

20x increased risk of Ankylosing Spondylitis.
Is agenotype
ofrs7743761
GeneDHFRP2
Chromosome6
Position31,368,323
mentionedby
Magnitude2
ReputeBad
Geno Mag Summary
(A;A) 2 20x increased risk of Ankylosing Spondylitis.
(A;C) 2 4.6x increased risk of Ankylosing Spondylitis.
(C;C) 1.9 Normal (lower) risk of Ankylosing Spondylitis.

Greatly increased odds (but still only about 2%) of this disease. Ankylosing Spondylitis is a rare autoimmune disease that causes inflammation of the spine and joints. The usual age of onset is from the late teens to 40 years of age. Some people with ankylosing spondylitis have onset of symptoms when younger than 16 years. This form of AS is referred to as juvenile-onset ankylosing spondylitis. Reference: http://www.emedicinehealth.com/ankylosing_spondylitis_rheumatologic_perspective/article_em.htm