Have questions? Visit https://www.reddit.com/r/SNPedia

rs7753394

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 1.5x risk of Crohn's disease
(C;T) 1.2x risk of Crohn's disease
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome6
Position137764111
is asnp
is mentioned by
dbSNPrs7753394
ebirs7753394
HLIrs7753394
Exacrs7753394
Varsomers7753394
Maprs7753394
PheGenIrs7753394
hapmaprs7753394
1000 genomesrs7753394
hgdprs7753394
ensemblrs7753394
gopubmedrs7753394
geneviewrs7753394
scholarrs7753394
googlers7753394
pharmgkbrs7753394
gwascentralrs7753394
openSNPrs7753394
23andMers7753394
23andMe allrs7753394
SNP Nexus

SNPshotrs7753394
SNPdbers7753394
MSV3drs7753394
GWAS Ctlgrs7753394
GMAF0.4343
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs7753394 has been reported in a large study to be associated with Crohn's disease.

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.21 (CI 1.04-1.40), and for homozygotes, 1.48 (CI 1.25-1.76). [PMID 17554300OA-icon.png]


[PMID 18438406OA-icon.png] Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.


[PMID 19956648OA-icon.png] Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.