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rs77571059

From SNPedia

Orientationplus
Stabilizedplus
Make rs77571059(-;-)
Make rs77571059(-;GGGGC)
Make rs77571059(GGGGC;GGGGC)
ReferenceGRCh38 38.1/141
Chromosome7
Position128937877
GeneIRF5
is asnp
is mentioned by
dbSNPrs77571059
ebirs77571059
HLIrs77571059
Exacrs77571059
Varsomers77571059
Maprs77571059
PheGenIrs77571059
hapmaprs77571059
1000 genomesrs77571059
hgdprs77571059
ensemblrs77571059
gopubmedrs77571059
geneviewrs77571059
scholarrs77571059
googlers77571059
pharmgkbrs77571059
gwascentralrs77571059
openSNPrs77571059
23andMers77571059
23andMe allrs77571059
SNP Nexus

SNPshotrs77571059
SNPdbers77571059
MSV3drs77571059
GWAS Ctlgrs77571059
Max Magnitude
a 5bp CGGGG indel upstream of IRF5/TNPO3, said to be causative and to explain the previously reported Lupus associations with rs2004640, rs10954213, and rs729302

[PMID 24350899] Molecular Effects of Autoimmune-Risk Promoter Polymorphisms on Expression, Exon Choice, and Translational Efficiency of Interferon Regulatory Factor 5

[PMID 24014567] A redundant epistatic interaction between IRF5 and STAT4 of the type I interferon pathway in susceptibility to lupus and rheumatoid arthritis