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rs776746(G;G)

From SNPedia

CYP3A5*3 homozygote; CYP3A5 non-expressor
Is agenotype
ofrs776746
GeneCYP3A5, ZSCAN25
Chromosome7
Position99,672,916
mentionedby
Magnitude2.5
ReputeBad
Geno Mag Summary
(A;A) 0 reference allele
(A;G) 2 carrier of 1 nonfunctional CYP3A5 allele; drug metabolism affects
(G;G) 2.5 CYP3A5*3 homozygote; CYP3A5 non-expressor

Impacts metabolism of tacrolimus, an immunosuppressive drug used in organ transplantation. This is the most common phenotype in caucasian and many other populations. Only in africans is expressing the gene common.