Have questions? Visit https://www.reddit.com/r/SNPedia

rs7799039

From SNPedia

Orientationplus
Stabilizedplus
Make rs7799039(A;A)
Make rs7799039(A;G)
Make rs7799039(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position128238730
is asnp
is mentioned by
dbSNPrs7799039
ebirs7799039
HLIrs7799039
Exacrs7799039
Varsomers7799039
Maprs7799039
PheGenIrs7799039
hapmaprs7799039
1000 genomesrs7799039
hgdprs7799039
ensemblrs7799039
gopubmedrs7799039
geneviewrs7799039
scholarrs7799039
googlers7799039
pharmgkbrs7799039
gwascentralrs7799039
openSNPrs7799039
23andMers7799039
23andMe allrs7799039
SNP Nexus

SNPshotrs7799039
SNPdbers7799039
MSV3drs7799039
GWAS Ctlgrs7799039
GMAF0.4334
Max Magnitude
? (A;A) (A;G) (G;G) 28

[PMID 19142102] Polymorphisms of the LEP- and LEPR gene and obesity in patients using antipsychotic medication.


[PMID 19921265] The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders



[PMID 20140086OA-icon.png] Genetic Variation at Selected SNPs in the Leptin Gene and Association of Alleles with Markers of Kidney Disease in a Xhosa Population of South Africa

[PMID 20183928] The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders


[PMID 20517895] Genetic variations of leptin and leptin receptor are associated with body composition changes in response to physical training

[PMID 20562674] Association between LEP and LEPR gene polymorphisms and dyslipidemia in patients using atypical antipsychotic medication

[PMID 20504252] Association of HTR2C, but not LEP or INSIG2, genes with antipsychotic-induced weight gain in a German sample


[PMID 21510767] Polymorphisms of the LEP-, LEPR and HTR2C gene: obesity and BMI change in patients using antipsychotic medication in a naturalistic setting


[PMID 22669627OA-icon.png] Polymorphisms in LEP and NPY genes modify the response to soluble fibre Plantago ovata husk intake on cardiovascular risk biomarkers


[PMID 15197684OA-icon.png] Common variants in the 5' region of the leptin gene are associated with body mass index in men from the National Heart, Lung, and Blood Institute Family Heart Study.


[PMID 17879022] Are common leptin promoter polymorphisms associated with restenosis after coronary stenting?


[PMID 18059035OA-icon.png] Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions.


[PMID 18923972] The -2548G/A LEP polymorphism is associated with blood pressure in Tunisian obese patients.


[PMID 18992263OA-icon.png] Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.


[PMID 19035456OA-icon.png] Adipokine genes and prostate cancer risk.


[PMID 19204185OA-icon.png] Leptin is associated with blood pressure and hypertension in women from the National Heart, Lung, and Blood Institute Family Heart Study.


[PMID 19337797] Association between variants in the genes for leptin, leptin receptor, and proopiomelanocortin with chronic heart failure in the Czech population.


[PMID 19593725OA-icon.png] Association of maternally inherited GNAS alleles with African-American male birth weight.


[PMID 19604093OA-icon.png] Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients.


[PMID 19623271OA-icon.png] A Bayesian hierarchical model for analysis of SNP diversity in multilocus, multipopulation samples.


[PMID 19942621OA-icon.png] An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6.


[PMID 20201642] Associations of polymorphisms in adiponectin and leptin genes with men's longevity.


[PMID 22020349] Polymorphisms of INSIG2, MC4R, and LEP are associated with obesity- and metabolic-related traits in schizophrenic patients.


GET Evidence
rs7799039
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.398438
summary



[PMID 23284729OA-icon.png] Aerobic Fitness Does Not Modify the Effect of FTO Variation on Body Composition Traits


[PMID 24146750OA-icon.png] Association of LEP G2548A and LEPR Q223R Polymorphisms with Cancer Susceptibility: Evidence from a Meta-Analysis


[PMID 22426215] Association study of polymorphisms in leptin and leptin receptor genes with antipsychotic-induced body weight gain.


[PMID 23433430] The impact of obesity-related SNP on appetite and energy intake.


[PMID 23754448] LEP gene variant is associated with prostate cancer but not with colorectal cancer.


[PMID 25810718OA-icon.png] Polymorphism in LEP and LEPR May Modify Leptin Levels and Represent Risk Factors for Thyroid Cancer


[PMID 26167411] Genetic variants in leptin: Determinants of obesity and leptin levels in South Indian population


[PMID 26192702] ADIPOQ-11377C>G Polymorphism Increases Risk of Adipokine Abnormalities and Child Obesity Regardless of Dietary Intake


[PMID 26407154] Evaluation of CYP17A1 and LEP Gene Polymorphisms in Breast Cancer