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rs7961894

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs7961894(C;T)
Make rs7961894(T;T)
ReferenceGRCh38 38.1/141
Chromosome12
Position121927677
GeneWDR66
is asnp
is mentioned by
dbSNPrs7961894
ebirs7961894
HLIrs7961894
Exacrs7961894
Varsomers7961894
Maprs7961894
PheGenIrs7961894
hapmaprs7961894
1000 genomesrs7961894
hgdprs7961894
ensemblrs7961894
gopubmedrs7961894
geneviewrs7961894
scholarrs7961894
googlers7961894
pharmgkbrs7961894
gwascentralrs7961894
openSNPrs7961894
23andMers7961894
23andMe allrs7961894
SNP Nexus

SNPshotrs7961894
SNPdbers7961894
MSV3drs7961894
GWAS Ctlgrs7961894
GMAF0.04224
Max Magnitude0
? (C;C) (C;T) (T;T) 28
[PMID 19110211OA-icon.png] rs7961894, rs12485738 and rs2138852 together accounted for 4%-5% of the variance in mean platelet volume, which is increased in myocardial and cerebral infarction and is an independent and strong predictor for postevent morbidity and mortality
OMIM612573
DescMEAN PLATELET VOLUME QUANTITATIVE TRAIT LOCUS 1; MPVQTL1
Variant
Relatedalso
GWAS snp
PMID [PMID 19820697OA-icon.png]
Trait MPV
Title A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
Risk Allele T
P-val 3E-44
Odds Ratio 0.03 [0.027-0.035] fl increase



GWAS snp
PMID [PMID 22139419OA-icon.png]
Trait
Title New gene functions in megakaryopoiesis and platelet formation.
Risk Allele C
P-val 1E-10
Odds Ratio 3.9230 None


GET Evidence
rs7961894
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.0546875
summary



GWAS snp
PMID [PMID 24026423OA-icon.png]
Trait Mean platelet volume
Title A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.
Risk Allele T
P-val 6E-38
Odds Ratio .31 [NR] unit decrease