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rs798766

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 1 Increased susceptibility urinary bladder cancer
Make rs798766(C;C)
Make rs798766(C;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position1732512
GeneTACC3
is asnp
is mentioned by
dbSNPrs798766
ebirs798766
HLIrs798766
Exacrs798766
Varsomers798766
Maprs798766
PheGenIrs798766
hapmaprs798766
1000 genomesrs798766
hgdprs798766
ensemblrs798766
gopubmedrs798766
geneviewrs798766
scholarrs798766
googlers798766
pharmgkbrs798766
gwascentralrs798766
openSNPrs798766
23andMers798766
23andMe allrs798766
SNP Nexus

SNPshotrs798766
SNPdbers798766
MSV3drs798766
GWAS Ctlgrs798766
GMAF0.2236
Max Magnitude1
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 20348956OA-icon.png]
Trait Urinary bladder cancer
Title A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer
Risk Allele T
P-val 1E-11
Odds Ratio 1.24 [1.17-1.32]

The T allele at rs798766 is associated with 1.24 higher odds of bladder cancer. [PMID 20348956OA-icon.png]

GWAS snp
PMID [PMID 20972438OA-icon.png]
Trait
Title A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
Risk Allele T
P-val 4E-13
Odds Ratio 1.2000 [1.14-1.26]
OMIM109800
Desc
Variant
Relatedalso
[PMID 21459758OA-icon.png] Chromosome 4p16.3 variant modify bladder cancer risk in a Chinese population.


[PMID 23053209] Genetic polymorphisms on 8q24.1 and 4p16.3 are not linked with urothelial carcinoma of the bladder in contrast to their association with aggressive upper urinary tract tumours


[PMID 22711262] Systematic evaluation of bladder cancer risk-associated single-nucleotide polymorphisms in a Chinese population.

GWAS snp
PMID [PMID 24163127OA-icon.png]
Trait Bladder cancer
Title Genome-wide association study identifies multiple loci associated with bladder cancer risk.
Risk Allele T
P-val 7E-25
Odds Ratio 1.22 [1.18-1.27]