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rs8023462

From SNPedia

Orientationplus
Stabilizedplus
Make rs8023462(C;C)
Make rs8023462(C;T)
Make rs8023462(T;T)
ReferenceGRCh38 38.1/141
Chromosome15
Position78622392
GeneCHRNA3
is asnp
is mentioned by
dbSNPrs8023462
ebirs8023462
HLIrs8023462
Exacrs8023462
Varsomers8023462
Maprs8023462
PheGenIrs8023462
hapmaprs8023462
1000 genomesrs8023462
hgdprs8023462
ensemblrs8023462
gopubmedrs8023462
geneviewrs8023462
scholarrs8023462
googlers8023462
pharmgkbrs8023462
gwascentralrs8023462
openSNPrs8023462
23andMers8023462
23andMe allrs8023462
SNP Nexus

SNPshotrs8023462
SNPdbers8023462
MSV3drs8023462
GWAS Ctlgrs8023462
GMAF0.2406
Max Magnitude
The (T;T) genotype (as published) of rs8023462 was calculated to represent a hazard ratio of 1.35 (CI: 1.08-1.70) for initiation of tobacco and alcohol use at an earlier age than average. A linked SNP also in the A5A3B4 gene, rs1948, showed similiar association. [PMID 18163978OA-icon.png]


[PMID 18165968OA-icon.png] Identification of pharmacogenetic markers in smoking cessation therapy.


[PMID 18571741OA-icon.png] Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.


[PMID 19330903OA-icon.png] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.


[PMID 19492010OA-icon.png] The genetic components of alcohol and nicotine co-addiction: from genes to behavior.


[PMID 23872218OA-icon.png] Functional characterization of SNPs in CHRNA3/B4 intergenic region associated with drug behaviors