rs80357327

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(A;T)	6	BRCA1 variant considered pathogenic for breast cancer
(T;T)	0	common in clinvar

Make rs80357327(A;A)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43115730

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357327
dbSNP (classic)	rs80357327
ClinGen	rs80357327
ebi	rs80357327
HLI	rs80357327
Exac	rs80357327
Gnomad	rs80357327
Varsome	rs80357327
LitVar	rs80357327
Map	rs80357327
PheGenI	rs80357327
Biobank	rs80357327
1000 genomes	rs80357327
hgdp	rs80357327
ensembl	rs80357327
geneview	rs80357327
scholar	rs80357327
google	rs80357327
pharmgkb	rs80357327
gwascentral	rs80357327
openSNP	rs80357327
23andMe	rs80357327
SNPshot	rs80357327
SNPdbe	rs80357327
MSV3d	rs80357327
GWAS Ctlg	rs80357327

Max Magnitude

6

23andMe name: i6008306

ClinVar
Risk	rs80357327(A;A) rs80357327(C;C) rs80357327(G;G)
Alt	rs80357327(A;A) rs80357327(C;C) rs80357327(G;G)
Reference	Rs80357327(T;T)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1 Hereditary cancer-predisposing syndrome not provided
Reversed	1
HGVS	NC_000017.10:g.41267747A>C; NC_000017.10:g.41267747A>G; NC_000017.10:g.41267747A>T
CLNSRC	Database of BRCA1 and BRCA2 sequence variants that have been clinically reclassified by a quantitative integrated evaluation
CLNACC	RCV000047411.2, RCV000047410.2, RCV000047409.2, RCV000111838.2, RCV000222092.1, RCV000444956.1,