rs80357525

minus

Geno	Mag	Summary
(-;AG)	6	BRCA1 variant considered pathogenic for breast cancer
(AG;AG)	0	common in clinvar

Make rs80357525(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43092201

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357525
dbSNP (classic)	rs80357525
ClinGen	rs80357525
ebi	rs80357525
HLI	rs80357525
Exac	rs80357525
Gnomad	rs80357525
Varsome	rs80357525
LitVar	rs80357525
Map	rs80357525
PheGenI	rs80357525
Biobank	rs80357525
1000 genomes	rs80357525
hgdp	rs80357525
ensembl	rs80357525
geneview	rs80357525
scholar	rs80357525
google	rs80357525
pharmgkb	rs80357525
gwascentral	rs80357525
openSNP	rs80357525
23andMe	rs80357525
SNPshot	rs80357525
SNPdbe	rs80357525
MSV3d	rs80357525
GWAS Ctlg	rs80357525

Max Magnitude

6

rs80357525, also known as 3448delAG, c.3329_3330delAG and p.Lys1110Thrfs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357525(-;-)
Alt	rs80357525(-;-)
Reference	Rs80357525(AG;AG)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41244218_41244219delCT
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000048146.2, RCV000077542.5,