rs80359159

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(C;C)	0	common in clinvar
(C;T)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359159(C;G)

Make rs80359159(G;G)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32379872

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359159
dbSNP (classic)	rs80359159
ClinGen	rs80359159
ebi	rs80359159
HLI	rs80359159
Exac	rs80359159
Gnomad	rs80359159
Varsome	rs80359159
LitVar	rs80359159
Map	rs80359159
PheGenI	rs80359159
Biobank	rs80359159
1000 genomes	rs80359159
hgdp	rs80359159
ensembl	rs80359159
geneview	rs80359159
scholar	rs80359159
google	rs80359159
pharmgkb	rs80359159
gwascentral	rs80359159
openSNP	rs80359159
23andMe	rs80359159
SNPshot	rs80359159
SNPdbe	rs80359159
MSV3d	rs80359159
GWAS Ctlg	rs80359159

Max Magnitude

6

rs80359159, also known as Q3026X, c.9076C>T and p.Gln3026Ter, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359159(G;G) rs80359159(T;T)
Alt	rs80359159(G;G) rs80359159(T;T)
Reference	Rs80359159(C;C)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32954009C>G; NC_000013.10:g.32954009C>T
CLNSRC	Ambry Genetics ClinVar
CLNACC	RCV000045705.3, RCV000114041.1, RCV000129636.2, RCV000031790.6, RCV000045706.3, RCV000131038.3, RCV000413921.1,