rs80359298

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(-;AA)	6	BRCA2 variant considered pathogenic for breast cancer
(AA;AA)	0	common in clinvar

Make rs80359298(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32316477

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359298
dbSNP (classic)	rs80359298
ClinGen	rs80359298
ebi	rs80359298
HLI	rs80359298
Exac	rs80359298
Gnomad	rs80359298
Varsome	rs80359298
LitVar	rs80359298
Map	rs80359298
PheGenI	rs80359298
Biobank	rs80359298
1000 genomes	rs80359298
hgdp	rs80359298
ensembl	rs80359298
geneview	rs80359298
scholar	rs80359298
google	rs80359298
pharmgkb	rs80359298
gwascentral	rs80359298
openSNP	rs80359298
23andMe	rs80359298
SNPshot	rs80359298
SNPdbe	rs80359298
MSV3d	rs80359298
GWAS Ctlg	rs80359298

Max Magnitude

6

rs80359298, also known as 245delAA, c.17_18delAA and p.Lys6Argfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359298(-;-)
Alt	rs80359298(-;-)
Reference	Rs80359298(AA;AA)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer not provided
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 not provided
Reversed	0
HGVS	NC_000013.10:g.32890614_32890615delAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000043891.2, RCV000113025.4, RCV000486492.1,