rs80359340

plus

Geno	Mag	Summary
(-;GACA)	6	BRCA2 variant considered pathogenic for breast cancer
(CAGA;CAGA)	0	common in clinvar
(GACA;GACA)	0	common in clinvar

Make rs80359340(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32337008

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359340
dbSNP (classic)	rs80359340
ClinGen	rs80359340
ebi	rs80359340
HLI	rs80359340
Exac	rs80359340
Gnomad	rs80359340
Varsome	rs80359340
LitVar	rs80359340
Map	rs80359340
PheGenI	rs80359340
Biobank	rs80359340
1000 genomes	rs80359340
hgdp	rs80359340
ensembl	rs80359340
geneview	rs80359340
scholar	rs80359340
google	rs80359340
pharmgkb	rs80359340
gwascentral	rs80359340
openSNP	rs80359340
23andMe	rs80359340
SNPshot	rs80359340
SNPdbe	rs80359340
MSV3d	rs80359340
GWAS Ctlg	rs80359340

Merged from

Rs760792406

Max Magnitude

6

rs80359340, also known as 2881del4, c.2653_2656delGACA and p.Asp885_Asn886?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359340(-;-) Rs80359340(CAGA;CAGA)
Alt	rs80359340(-;-) Rs80359340(CAGA;CAGA)
Reference	Rs80359340(GACA;GACA)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32911145_32911148delGACA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044033.2, RCV000113073.3, RCV000162913.2, RCV000485965.1,