rs80359365

plus

Geno	Mag	Summary
(-;-)	0	common/normal
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(-;AAAA)	6	BRCA2 variant considered pathogenic for breast cancer
(-;G)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Reference

GRCh38 38.1/141

Chromosome

13

Position

32337312

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359365
dbSNP (classic)	rs80359365
ClinGen	rs80359365
ebi	rs80359365
HLI	rs80359365
Exac	rs80359365
Gnomad	rs80359365
Varsome	rs80359365
LitVar	rs80359365
Map	rs80359365
PheGenI	rs80359365
Biobank	rs80359365
1000 genomes	rs80359365
hgdp	rs80359365
ensembl	rs80359365
geneview	rs80359365
scholar	rs80359365
google	rs80359365
pharmgkb	rs80359365
gwascentral	rs80359365
openSNP	rs80359365
23andMe	rs80359365
SNPshot	rs80359365
SNPdbe	rs80359365
MSV3d	rs80359365
GWAS Ctlg	rs80359365

Max Magnitude

6

rs80359365, also known as c.2954_2957delAAAA, c.2957delA, 3185insG, c.2957_2958insG, c.2957dupA and p.Asn986?fs, represents at least three variants in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	Rs80359365(A;A) rs80359365(G;G)
Alt	Rs80359365(A;A) rs80359365(G;G)
Reference	Rs80359365(-;-)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32911449_32911450insG; NC_000013.10:g.32911449dupA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031392.6, RCV000131097.3, RCV000463291.1, RCV000482218.1, RCV000044094.4, RCV000077700.5, RCV000160274.3, RCV000213454.1,